Possible endurance boosters can be detected on test
by admin ~ July 30th, 2009.
A class of compounds called benzothiazepine has been reportedly emerging and might be out in the market soon. However, current standard testing still cannot trace this particular class of compounds. These compounds are in the early stages of development and have not even been tested on humans, although it already underwent several trials using animals.
Benzothiazepines are currently used in treating heart disorders like angina (chest pain). They act by preventing protein channels from leaking out calcium inside the muscles. Calcium is primarily needed by all types of muscles in producing contractions, and when it gets out of the muscle, weakening and fatigue can occur.
Using high resolution mass spectrometry, researchers can detect the compounds, JTV-519 and S-107, even at low urine concentrations of 0.1 nanograms per milliliter.
Mario Thevis, Director of the Center for Preventive Doping Research at the German Sport University of Cologne, Germany and his colleagues obtained a molecular “fingerprint” of these compounds. They determined the compound’s molecular weight and structure.
The study’s aim is to prevent future misuse of this compound in sports. It will enable sports officials to prepare before it is officially launched in the market.
According to Mario Thevis from Science Daily:
Category: Anabolic Steroids | Tags: Benzothiazepine, calcium, JTV-519, S-107“We used the common approaches that are employed for detecting anabolic agents. Our work showed that we could identify the right compounds and that we have a sensitive test,” says Thevis.